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Anti-Inflammatory Drug Pharmacetical Raw Materials Miconazole Nitrate

1.0 USD
Min. Order: 10 Gram
Trade Term: FOB,CIF
Payment Terms: WU, Money Gram, T/T, BItcoin
Supply Ability: 5000kg per month
Place of Origin: Hubei

Company Profile

Location: Wuhan, Hubei, China (Mainland)
Business Type: Manufacturer, Trading Company

Product Detail

Model No.: pharma raw powder
Means of Transport: Ocean, Air, express
Brand Name: Miconazole Nitrate
CAS No.: 22832-87-7
Purity: 99%
Miconazole Nitrate color: white
Miconazole Nitrate appearence: powder
Miconazole Nitrate Alias: diclophenacsodium;gp45840;huma-difenac
Miconazole Nitrate MF: C18h15cl4n3o4
Miconazole Nitrate EINECS: 245-256-6
Miconazole Nitrate Usage: aAntifungal;Aromatics;Heterocycles;
Miconazole Nitrate payment methods: T/T, Westeron Union, Money Gram, Bitcoin
Miconazole Nitrate lead time: within 24hour after payment confirmed
Miconazole Nitrate Standard: USP39
Miconazole Nitrate Delivery time: 5-7 days
Production Capacity: 5000kg per month
Packing: disguised package
Delivery Date: within 24 hours after payment confirmed
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Product Description

Anti-Inflammatory Drug Pharmacetical Raw Materials Miconazole Nitrate 

Top Quality Pharmacetical Raw Powder CAS 22832-87-7 Miconazole Nitrate 


Miconazole nitrate

Cas:22832-87-7

Mf:C18h15cl4n3o4

Mw:479.14

Einecs:245-256-6

Assay:99%

Chemical Properties:White powder

Packing:25kg/paper barrel

Product categories:Antifungals;Antifungal;Aromatics;Heterocycles;

Usage:Antifungal (topical).  An antifungal agent that inhibits platelet cyclooxygenase.

Biological Activity:Antifungal agent. Inhibits lanosterol demethylase and induces formation of reactive oxygen species.


Miconazole nitrate Descrption


Miconazole nitrate is a kind of antifungal agent which is the drug "Dakelin" which we are familiar with as commonly used drug for treating skin ringworm. It has various kinds of effects. It inhibit the biosynthesis of ergosterol which is the fungal cell membrane component, causing damage to the cell membrane structure, increasing the membrane permeability, resulting in the leakage of the intracellular components and inhibiting the glucose utilization, preventing the nutrient uptake, and finally leading to fungal cell death.



Miconazole nitrate Application


Miconazole nitrate is therefore suitable for the treatment of tinea, jock itch, ringworm, athlete's foot, tinea versicolor and paronychomycosis as well as the vaginal infection and secondary infection caused by the yeast (such as Candida) and Gram-positive bacteria.


Miconazole nitrate is also effective in treating otitis externa and bacterial skin infections.The common adverse reactions and side effects of miconazole nitrate include: occasional allergy, blisters, burning feeling, redness, itching or other skin irritation. Very rare angioedema, urticaria, eczema, contact dermatitis, erythema, pelvic pain (cramps), vaginal irritation, vaginal secretions and discomfort in the administration site.


Miconazole nitrate Specification


ItemsSpecificationsResults
AppearanceWhite or white crystalline powderComplies
IdentificationInfrared absorption and standardComplies
Solution claritySolution is clear, color is not deep in the standard Y7Complies
Solubility

Difficult to dissolve in water, soluble in ethanol

, slightly soluble in ethanol

Complies
Impurity A≤0.25%0.07%
Impurity B≤0.25%0.07%
Impurity C≤0.25%0.05%
Impurity D≤0.25%0.04%
Impurity E≤0.25%0.03%
Impurity F≤0.25%N/A
Impurity G≤0.25%N/A
Individual unspecified impurity≤0.1%0.02%
Total Impurities≤0.5%0.29%
Melting Point178-184℃181.8-182.6℃
Loss On Drying≤0.5%0.21%
Residue on ignition≤0.1%0.05%
Toluene≤890ppm110ppm
Ethanol≤5000ppm110ppm
Benzyl chloride≤1000ppm100ppm
2,4-Dichlorobenzyl chloride≤1000ppmND
Assay(On Dry Basis)98.5-101%99.50%
ConculsionThe results can conform to the USP39 Standard


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