Antibacterial Agent Terbinafine HCl Terbinafine Hydrochloride raw powder CAS 78628-80-5
Terbinafine Hcl Product Name: Terbinafine Hydrochloride
Terbinafine Hcl CAS: 78628-80-5
Terbinafine Hcl MF: C21H26ClN
Terbinafine Hcl MW: 327.89
Terbinafine Hcl EINECS: 245-385-8
Terbinafine Hcl Product Categories: Antifungal;APIs;Acetylenes;Antifungals for Research and Experimental Use;Biochemistry;Functionalized Acetylenes;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Terbinafine;LAMISIL
Terbinafine Hcl Melting point : 204-208°C
Terbinafine Hcl Storage temp. : -20°C Freezer
Terbinafine Hcl Chemical Properties : Crystalline Powder
Terbinafine Hydrochloride intruduction
Terbinafine Hydrochloride is broad-spectrum allylamines antifungal drug.Selectively inhibits fungal squalene ring oxidase activity, make the fungal cell membrane in the process of the composition of squalene epoxidation reaction, thus to kill or inhibit the action of the fungus.Suitable for treatment of candidiasis skin, such as tinea manuum, tinea, tinea, ringworm of the body, tinea versicolor, also is the best medicine for the treatment of this.
Terbinafine Hydrochloride Applications
1, Treating hair and skin infections caused by trichophyta(red hair versicolor bacterium, tinea versicolor bacterium, verrucous versicolor bacterium, tinea capitis and purple hair ringworm fungi, etc),microsporum canis,Epidermophyton floccosum,etc
2, All kinds of tinea disease (ringworm of the body, tinea, tinea manus and tinea capitis, etc.) and by candida (candida albicans, etc.) caused by yeast infections of the skin
3, Caused by skin mold onychomycosis (nail fungus infection)
1.Skin, hair and nail infection caused by Btrichophyta (white hair versicolor bacterium, Trichophyton mentagrophytes, Trichophyton verrucosum, trichophyton tonsurans and Trichophyton violaceum, etc.), microsporum canis, epidermophyton floccosum, ect.
2.Skin yeast infections caused by all kinds of tinea disease (ringworm of the body, tinea, tinea manus and tinea capitis, etc.) and candida (candida albicans, etc.).
3.Onychomycosis (nail fungus infection) caused by molds.
Usage and Dosage:
1.Local external use: apply adequate amount to the affected area and its surrounding, 1-2 times a day. Ringworm of the body, 2-4 weeks, tinea of feet and hands, tinea versicolor, 4 to 6 weeks.
2.Oral: 0.25 grams each time for adult, once per day, period of treatment is as follows:
Skin infection treatment: tinea of feet and hands [toe (means) and plantar]: 2 ~ 6 weeks; Ringworm of the body, tinea, 2 ~ 4 weeks.
3.Skin candidiasis: 2 ~ 4 weeks. normal skin appearance and loss of infection can only be visible in a few weeks for curing.
4.Hair and scalp infection treatment: tinea capitis: 4 weeks, tinea capitis most happen in children.
Onychomycosis: The most treatment course of patients is 6 weeks to three months. Young patients with normal growth can shorten the treatment course, and less than 3 months of treatment may be enough in addition to the thumb (foot) armour.
5.In other cases, the treatment is usually 3 months. Some patients, especially whose thumb (toe) infected, may take 6 months or longer. The treatment may take more than 3 months if the nail grew slowly in the first week. In healing of mycology and stopping for a few months after treatment, the continuous improvement of nail appearance then completely normal can be seen, this is because that the healthy tissue growth needs time.
Terbinafine Hydrochloride COA
|Product name||Terbinafine HCL|
|CAS No.||78628-80-5||Outer Packing||25KG/drum|
|Production date||2015.04.14||Shelf life||2018.04.13|
|Items of analysis||Specification||Results|
|Appearance||White or off-white powder||Comply|
|Solubility||Very slightly or slightly soluble in water,||Comply|
|Single unknown impurity||≤0.10%||0.05%|
|Loss on drying||≤0.5%||0.17%|
|Residue on ignition||≤0.1%||0.05%|
|i-propanol||≤ 2000 ppm||Comply|
|≤ 2000 ppm||Comply|
|Storage||Keep tightly closed. Store in a cool dry place.||Keep tightly closed. Store in a cool dry place|