|Min. Order:||10 Gram|
|Payment Terms:||WU, Money Gram, T/T, bitcoin|
|Place of Origin:||Shanghai|
|Location:||Shanghai, China (Mainland)|
|Means of Transport:||Land, Ocean, Air|
|Storage:||Shading, confined preservation|
|Payment Terms:||Wester Union,Money Gram,Bank Transfer,T/T|
|Shipment:||EMS, DHL, FedEx, TNT|
|Certification:||GMP, HSE, ISO 9001, USP, BP|
|Leading Time:||About 5~8 working days|
|Delivery Date:||Within 12hour|
MK-677/Ibutamoren Mesylate CAS:159752-10-0
Alias: Ibutamoren, MK-677, MK-0677, L-163,191, L163191, Nutrobal
Melting Point: 156 – 158 °C
Solubility: Water, DMSO, Ethanol, Propylene Glycol
Storage: at 20 °C 2 years, minimize open air exposure, store in a cool dry place
General information of Ibutamoren Mesylate (MK-677):
MK-677 has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels.
It is currently under development as a potential treatment for reduced levels of these hormones, such as in growth hormone deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly.
It also alters metabolism of body fat and so may have application in the treatment of obesity.
MK-677(Ibutamoren Mesylate) Athletic Uses:
1. Fat loss
2. Muscle gain
3. Injury healing and bone strengthening
How does MK-677 Works ?
Growth hormone pulse intensity can be increased through 4 possible mechanisms:
1. Increasing GHRH (growth hormone releasing hormone) release.Amplifying GHRH signaling in somatotrophs of the anterior pituitary gland.
2. Reducing somatostatin release (somatostatin turns off GH release).Inhibiting of somatostatin receptor signaling.
3. Nutrobal (Mk-677) was found to work through all four of these mechanisms. After ingestion, Growth Hormone (GH) was shown to increase dose dependently, at doses starting at 5 milligrams (mgs) a day.