Ibuprofen Coated Medicinal Tablets Antipyretic - analgesic 10*10's / Box

 200MG 400MG Ibuprofen Coated Medicinal Tablets Antipyretic - analgesic 10*10's / Box

IBUPROFEN COATED Tablets 400MG

COMPOSITION:

Each sugar-coated tablet contains 400 mg Ibuprofen.
 

PHARMACOLOGICAL ACTION:

Ibuprofen, which is a non-steroidal, anti-inflammatory, antipyretic and analgesic agent. It inhibits the synthesis of prostaglandins. Ibuprofen is absorbed from the gastro-intestinal tract producing peak plasma concentrations after one to two hours. 

INDICATIONS:

Ibuprofen is indicated in the treatment of rheumatoid arthritis, osteo-arthritis and ankylosing spondylitis, Still's disease (juvenile rheumatoid arthritis), fibrositis, musculoskeletal pain, swelling and inflammation due to trauma.

CONTRA-INDICATIONS:

It should be given with care to patients with peptic ulceration or a history of such ulceration, bleeding disorders, cardiovascular disease and those on oral anticoagulants. It should not be given to patients who are sensitive to aspirin. Ibuprofen should be administered with care in patients with asthma, especially those who have developed bronchospasm with other non-steroidal agents. 

WARNINGS:

Contains tartrazine, which may cause allergic type reactions (including bronchial asthma) in certain individuals. The overall incidence of tartrazine sensitivity is low; it is however frequently seen in patients who also have aspirin sensitivity.

DOSAGE AND DIRECTIONS FOR USE:

Adults:
600 mg - 1 200 mg daily in divided doses. 
Children:
20 mg/kg body mass per day but not to exceed 500 mg per day in children weighing less than 30 kg.

SIDE EFFECTS AND SPECIAL PRECAUTIONS:

Ibuprofen may cause nausea, vomiting, dyspepsia, diarrhoea, stomatitis, or gastrointestinal haemorrhage. Headache, dizziness, nervousness and other central nervous system effects, skin rash, thrombocytopenia, agranulocytosis, toxic amblyopia, bronchospasm, oedema, tinnitus, pruritus, depression, drowsiness, insomnia and blurred vision may occur.

PREGNANCY AND LACTATION:
Ibuprofen should not be administered during pregnancy and is not recommended for use by breast-feeding women. 
Regular use of NSAIDs during the third trimester of pregnancy may result in premature closure of the foetal ductus arteriosus in utero and possibly in persistent pulmonary hypertension of the newborn. The onset of labour may be delayed and its duration increased.

STORAGE INSTRUCTIONS:
Store below 25°C. Keep out of reach of children.