Pilot scale HPLC system High Performance Liquid Chromatography HPLC with ID 50 column

Pilot scale HPLC system High Performance Liquid Chromatography HPLC with ID 50 column

Description:

Equipped with a dynamic axial compression column 50mm pilot scale systems, preparative column and packed column system with integrated design, column packing process is very simple,10μm filler analytical column can reach almost the same high column efficiency, cargo is loaded can preparative column online use, without loading and unloading, and remain within the column bed axial dynamic pressure, to maintain the column bed long-term stability and efficiency, a single sample volume can be better achieved gram, this product is ideal for universities, drug plants, research institutes and other monomer purification for structural identification.

Applications:

Purify products from micro gram level to gram level

1. High throughput screening active substance in drug development (phytomedicinem, microbial fermentation drug, synthetic drugs etc.)
2. Standard substance and reference substance preparation
3. Laboratory scale purification in research institute: from micro gram level to gram level
4. Purify impurities in drugs
5. Explore purification method for large scale purification

Technical parameter:

• Column

Column Tube Diameter: 50 mm, length 500 mm (standard)

Column Pipe Material: 316 L stainless steel

Wall Roughness: Ra ≤ 0.4μm

Piston Material: 316 L stainless steel

Sieve Material: 316 L stainless steel, aperture: 3 - 5 μm

Maximum Pressure: 10 MPa

Pressure Demand: ≥ 0.8 MPa

Gas Demand: ≥ 3 m3

• Pump

Infusion Working Mode: Dual piston reciprocating pump

Pump Head: 100 mL or 250 mL Stainless steel pump head

Max Working Pressure: 20 MPa

Flow Rate Range: ( 0 ~ 100 ) mL / min or ( 0 ~ 250 ) mL / min

Flow Accuracy: ± 1.5 %

Flow Repeatability: RSD ≤ 1.0 %

Working Mode: Isocratic or Gradient Mode

• Detector

Wavelength Range: (190 - 700 ) nm

Light Source: D2 lamp (standard configuration), Tungsten lamp (optional available)

Wavelength accuracy: ± 2nm,

Wavelength repeatability: 0.4 nm

Detection Range: ( 0~2 ) AU

Baseline Noise: 3 X 10-5 AU

Baseline Drift: 1 X 10-3 AU/h

Competitive Advantage:

• Column packing convenience, the operator can own column packing.
• Column efficiency keep for a long time, long service life of chromatographic column.
• The sample volume can reach gram.
• Easy to move the entire system can be adapted to different locations experimental work.
• Dynamic axial compression columns can be customized according to user needs.
• Injection mode is optional for separate injection pump or injection valve.
• Maximum and minimum pressure adjustable, higher than the maximum pressure immediately stop the pump, the pressure below the minimum delay 2min automatically stops the pump.
• According to user needs configure automatic or manual collection device.