Galanthamine Hydrobromide
1500.0~1800.0 USD
| Min. Order: | 2 Kilogram |
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| Trade Term: | FOB |
| Payment Terms: | L/C, T/T |
| Place of Origin: | Hunan |
Company Profile
| Location: | China (Mainland) |
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| Business Type: | Manufacturer, Trading Company |
Product Detail
| Means of Transport: | Air |
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| Packing: | cardboard drum or as per buyer |
| Delivery Date: | 3days after received the deposit |
Product Description
Specification:99% | |
Synonym(s) :Reminyl, Nivalin | |
Chemical Name:(4aS,6R,8aS)-6-Hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-benzofuro[3a,3,2-e,f][2]benzazepine hydrobromide | |
Test Method:HPLC | |
Molecular Formula:C17H21NO3.HBr;C17H22BrNO3 | |
Molecular Weight:368.27 | |
CAS No.: 1953-04-4 EINECS No.: 217-780-5 Melting Point : 258~264 ℃ Solubility: Soluble in water,and slightly in alcohol. Appearance: White to whitish crystal powder, oderless and tasteless. Pharmacology Action: Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially, Galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.e. neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy. Galanthamine extract is a product with broad therapeutic index, allowing "soft" manifestation of its effect with individual dosing depending on the particular case. Several trials already showed that Galantamine 16 and 24 mg/day significantly benefits the cognitive, functional, and behavioral symptoms of AD as compared with placebo and proved also to be very effective in symptomatic treatment of senile dementia of Alzheimer's type. |
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